Methrandoplex-20 does not react strongly with the androgen receptor, instead relying on activity not mediated by the receptor for its effects these include dramatic increases in protein synthesis, glycogenolysis and muscle strength over a short space of time. In high doses (30 mg or more per day), side effects such as gyndecomastia, high blood pressure, acne and male pattern baldness may begin to occur. The drug causes severe masculinising effect in women even at low doses. Without the administration of aromatase inhibitors, estrogenic effect will appear over time in men. Many users will combat the estrogenic side effects with Tamoxifen or clomid.
The 17- methylation of the steroid does allow it to pass through the liver without being broken down allowing it to be taken orally. it also has the effect of decreasing the steroid´s affinity for sex hormone biding globulin, a protein that de-activates steroid molecules and prevents them from futher reactions with the body. As a result, Methandroplex-20 is significantly more active than an equivalent quantity of testosterone, resulting in rapid growth of muscle tissue. However, the concomitant elevation in estrogen levels – a result of the aromatization of MEthandroplex-20 – results in significant water retention. This gives the appearance of great gains in mass and strenght, wich prove to be temporary once the steroid is discontinued and water weight drops. Because of this, it is often used by bodybuilders only at the start of a “Steroid cycle” to facilitate rapid strength increases and apparance of great size, while compounds such as Testoplex-E300 or Decaplex-300 with long acting esters build up in the body to an appreciable amount capable of supporting anabolic function on their own.
Packaging: Each contains 100 tabs/20 mg